NRG NCORP Solicits PILOT Projects for NRG NCORP Cancer Prevention Control (CPC) Priorities

February 18 2022

Date Issued: February 18, 2022
Submission Due Date: April 22, 2022

Reply to: fielde@nrgoncology.org

Summary
NRG Oncology NCORP is soliciting PILOT projects for applications focused on NRG NCORP CancerPrevention and Control (CPC) priorities that will provide data that will directly lead to future Phase II-IIICPC concepts. As put forward in our core grant, CPC priorities for funding include cancer preventionresearch and cancer control investigation aimed at understanding and/or ameliorating the symptomsand toxicity related to: 

  • Neurocognitive function 
  • Gender specific symptom reduction 
  • Behavioral interventions 
  • Treatment dose alterations or delivery 
  • Cancer risk reduction 
  • Chemotherapy induced peripheral neuropathy 

Integral to these priorities, are the establishment of biospecimen repositories for molecular studies andapplications addressing/prioritizing health disparities, the elderly, racial and ethnic minorities, sexualand gender minorities, and rural residents. 

Funding can be requested for up to $50,000 and is contingent upon project review by NCORP leadersand NRG Oncology’s receipt of the Notice of Award from the Division of Cancer Prevention. One to twoprojects may be funded. Projects are to be implemented September 1, 2022 and completed byDecember 31, 2023. No carry over funds will be issued. An interim progress report is due within 6months of starting the project and a completed progress report is due at the end of the project period. Please work with your institution's Sponsored Research Office (SRO) in developing the project budgetand ensure that the SRO has approved the application and budget. If your project is funded, a subaward agreement with terms and conditions of the award will be issued to the institution. Funds willbe reimbursed upon receipt of invoices with subsequent payments upon review and approval of first 6months of the project. Applications from institutions that are able to waive indirect costs and/or providecost sharing, while not mandatory, will be prioritized. Applications from junior investigators withqualified mentors and those from minority backgrounds will also be prioritized. 

Background
The NRG NCORP core grant focuses on continued leadership in cancer prevention and control (CPC)research. Our CPC objectives will benefit the NCTN Program through continued research across thebreadth of NRG disease sites with a unique focus in both women's health, attributable to ourgynecologic and breast cancer expertise, and technology assessment, through the world's largestradiotherapy (RT) focused research base. CPC will design and conduct trials to assess cancer prevention,reduce the burden of cancer treatment-related symptoms across solid tumor disease sites with anemphasis on the prevention of women's cancers, and a focus on high prevalence symptoms in ourpopulation. 

Instructions for Applicants 
If you have an interest in this application, please submit a 3-4-page proposal to fielde@nrgoncology.org by 5pm ET, Friday, April 22, 2022. This opportunity is open to all investigators. Proposals should include: 

  • Title page (not part of the page limit) that indicates the title of the proposal, the leadinvestigator and all co investigators to include institutional affiliations and contact information
  • A description of the project, including summary of specific aims, expected outcomes, sufficientmethods to assess feasibility, and how this pilot project will lead to an NCORP concept (includebrief design). 
  • A detailed description of how the project will help lead to a Phase II or Phase III NCORPconcept 
  • An outline of NRG Oncology resources requested (i.e. biospecimen materials, statistical support,etc.) Any expenses related to these resources should be outlined in the budget 
  • One-page letter of support signed with the department chair specifically stating they will or willnot wave F&A and cost share [not included in the 3-4 page limit] 
  • Timeline for the project [not included in the 3-4 page limit] 
  • NIH biosketch of PI [not included in the 3-4 page limit] 
  • A detailed budget [not included in the 3-4 page limit]
    • Budget should be divided by Year 1 (Sept 1, 2022 – August 31, 2023) and Year 2 (Sept 1,2023 – December 31, 2023). Any salary must be at or below NIH cap. 

Submit applications to:
Erica Field, MPH, MHA
NCORP Administrator
fielde@nrgoncology.org
215-940-8824 

Direct scientific questions to NRG NCORP PI and CPC Chairs:
Deborah Watkins Bruner, RN, PhD, FAAN
NCORP PI
deborah.w.bruner@emory.edu

Joan Walker, MD
NCORP PI
Joan-Walker@ouhsc.edu

Lisa Kachnic, MD
NCORP Associate ChairChair, Cancer Control
lak2187@cumc.columbia.edu

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