Patient Study Materials

NRG Oncology has created website pages and brochures specific to certain NRG Oncology studies that are open to patient enrollment. These pages include overview information on the specific study, links for study locations and other relevant trials, frequently asked questions, and eligibility information.

Always Speak to Your Provider Regarding Decisions Pertaining to Your Healthcare
Please note that the goal of these materials is to educate and inform about NRG Oncology trials. The information available on our website is not a substitute for medical advice. Your healthcare team is the best source for information about your treatment options, including cancer clinical trials. Please take any information you collect to your doctor to discuss your questions and concerns.

 

Cancer Type Title (Patient Study Webpage) Status Brochure Study Results
Non-small Cell Lung CancerAdding high-dose, targeted radiation to the usual treatment for locally-advanced, inoperable non-small cell lung cancer Currently Available for Patients Download Brochure
Small CellCan adding radiation to immune therapy help improve survival for people with extensive stage small cell lung cancer?Currently Available for Patients Download Brochure
MesotheliomaTesting the addition of targeted radiotherapy to surgery & the usual systemic therapy for malignant pleural mesotheliomaCurrently Available for Patients Download Brochure
Small CellChemotherapy with or without the immunotherapy drug atezolizumab in people with limited stage small cell lung cancerCurrently Available for Patients Download Brochure
Non-small Cell Lung CancerTargeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung CancerCurrently Unavailable for Patients
Head and NeckTesting the Addition of Relatlimab to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal CancerCurrently Available for Patients Download Brochure
Head and NeckComparing a study drug to the usual treatment for people with metastatic HER2-positive salivary gland cancer that cannot be removed by surgeryCurrently Available for Patients Download Brochure
Head and NeckComparing two cisplatin dosing schedules combined with radiation for patients with advanced head and neck cancerCurrently Available for Patients Download Brochure
Head and NeckDoes Sentinel Lymph Node Biopsy improve survival outcomes when compared to Elective Neck Dissection for early stage oral cavity cancer?Currently Available for Patients Download Brochure
Head and NeckTesting less intensive radiation therapy with immunotherapy to treat selected low-risk patients with HPV-positive oropharyngeal cancerCurrently Unavailable for Patients Download Brochure
Head and NeckIndividualized treatment for nasopharyngeal cancer based on the patient’s DNACurrently Unavailable for Patients Download Brochure
OvarianA clinical trial for patients with recurrent adult type granulosa cell tumors of the ovaryCurrently Unavailable for Patients Download Brochure
Uterine CorpusTailoring Therapy in Post-surgical Patients with Low-risk Endometrial Cancer Currently Available for Patients
Uterine CorpusA clinical trial for patients with clear cell or endometrioid ovarian or endometrial cancer which has returned or spread after other treatmentsCurrently Available for Patients Download Brochure
Uterine CorpusA clinical trial for patients with Grade 1 or 2 endometrial cancer which has returned or spread after other treatmentsCurrently Available for Patients Download Brochure
Uterine CorpusA clinical trial for patients diagnosed with HER2-positive Uterine CancerCurrently Available for Patients Download Brochure
ProstateTesting shorter duration radiation therapy versus the usual radiation therapy in patients with high-risk prostate cancerCurrently Available for Patients Download Brochure
OtherCan adding radiation therapy to the usually prescribed immune therapy increase the time without your renal cell cancer getting worse or requiring surgery?Currently Available for Patients Download Brochure
ProstateCan the drug relugolix combined with radiation improve outcomes for men with limited metastatic “oligometastatic” prostate cancer?Currently Available for Patients Download Brochure
ProstateCan gene risk based on the Decipher risk score inform hormonal therapy treatment with radiation for unfavorable intermediate risk prostate cancer?Currently Available for Patients Download Brochure
ProstateThe PREDICT-RT Trial: Testing Hormone Therapy Treatment to Improve Outcomes for Men with High-risk Prostate Cancer Categorized by Low or High Gene Risk ScoreCurrently Available for Patients Download Brochure
ProstateDoes adding a study drug to usual therapy after radical prostatectomy delay the spread of prostate cancer?Currently Available for Patients Download Brochure
ProstateTesting reduced duration radiation therapy versus standard duration radiation therapy for prostate cancerCurrently Unavailable for Patients Download Results
ColorectalCIRCULATE-NORTH AMERICA: Colon Adjuvant Chemotherapy based on Evaluation of Residual DiseaseCurrently Available for Patients Download Brochure
EsophagealComparing proton to photon radiation therapy for esophageal cancerCurrently Available for Patients Download Brochure
ColorectalThe COBRA Study: Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After SurgeryCurrently Unavailable for Patients Download Brochure
ColorectalThe COMMIT Study: Comparing the Addition of the Drug Atezolizumab to the Usual Treatment Approach for Colorectal CancerCurrently Available for Patients Download Brochure
LiverComparing Proton Therapy to Photon Therapy for Liver Cancer
Currently Available for Patients Download Brochure
OtherManaging Symptoms and Psychological Distress During Oral Anti-Cancer TreatmentCurrently Available for Patients Download Brochure
OtherA study to examine computerized training to improve concentration, learning new things, and remembering in breast cancer survivors.Currently Available for Patients Download Brochure
OtherTesting Two Different Radiation Therapy Types to See Which Is Better at Preventing Loss of Memory and Changes in Thinking Ability for People with SCLC that Has Spread to the BrainCurrently Available for Patients Download Brochure
OvarianSOROCk: Comparing the Effects of Two Surgical Procedures in Ovarian Cancer Risk Reduction in Women with BRCA1 MutationsCurrently Available for Patients Download Brochure
Colorectal(FORTE) A study to determine whether a colonoscopy should be done every 5 years or every 10 years in people with 1 or 2 small growths (polyps) removed from their colonCurrently Available for Patients Download Brochure
OtherComparing Two Dose Levels of Bupropion Versus Placebo for Sexual DesireCurrently Unavailable for Patients Download Results
OtherTesting Whether Avoiding the Hippocampus in Addition to Memantine During Whole-Brain Radiation Therapy Better Prevents Cognitive Side Effects in People With Brain Metastases
Currently Unavailable for Patients Download Results
BreastTesting the addition of chemotherapy to the usual treatment of ovarian function suppression plus hormonal therapy in premenopausal ER-positive/HER2-negative breast cancer patients who are at high risk of cancer returningCurrently Available for Patients Download Brochure
BreastTesting the usual treatment of radiation therapy and HER2-targeted therapy to HER2-targeted therapy alone for low-risk HER2-positive breast cancerCurrently Available for Patients Download Brochure
BreastThe DEBRA Trial: De-escalating Breast Radiation After Lumpectomy for Low Risk, Estrogen Receptor Positive, Breast Cancer
Currently Available for Patients Download Brochure
Brain MetsComparing the addition of radiation either before or after surgery for patients with brain metastasesCurrently Available for Patients Download Brochure
Malignant GliomaCan a Second Chemotherapy Drug in Addition to Standard Radiation and Temozolomide Extend Your Life or Prevent the Growth and Spread of Your Brain Tumor?Currently Available for Patients Download Brochure
OtherComparing whole brain radiotherapy using a technique that avoids the hippocampus to stereotactic radiosurgery in people with cancer that has spread to the brain and come back in other areas of the brain after earlier stereotactic radiosurgeryCurrently Unavailable for Patients Download Brochure
Lower Grade GliomaComparing Proton Therapy to Photon Therapy for Low to Intermediate Grade GliomasCurrently Unavailable for Patients Download Brochure
Benign Brain TumorsComparing Observation Versus Radiation for Newly Diagnosed Grade II Meningiomas That Appear to Have Been Completely Removed Through Surgery Currently Available for Patients Download Brochure
MultipleTesting the use of neratinib or the combination of neratinib and palbociclib targeted treatment for HER2+ gynecologic and other solid tumors Currently Available for Patients Download Brochure
MultipleTesting the use of the combination of selumetinib and olaparib or selumetinib alone targeted treatment for RAS pathway mutant recurrent or persistent ovarian and endometrial cancersCurrently Available for Patients Download Brochure
BreastTesting the use of fulvestrant and binimetinib targeted treatment for NF1 mutation in hormone receptor-positive metastatic breast cancerCurrently Available for Patients Download Brochure