A Focus On Science
NRG Oncology and its partners have more than 150 years experience in conducting practice-defining, multi-institutional phase II and III trials sponsored primarily by the National Cancer Institute (NCI), as well as a history of undertaking the kind of phase I trials and translational biological studies that will be imperative for future clinical cancer research.


Our Mission
Improve the lives of patients with cancer by conducting practice-changing multi-institutional clinical and translational research
Dr. Robert S. Mannel
Our exceptional network brings individuals together who are passionate about changing the future of cancer care through impactful clinical trials.

Membership Resources
NRG Oncology’s membership roster is comprised of over 1,000 member sites including institutions on five continents. Our investigators represent all of the oncologic medical specialties and disciplines.
Learn MoreLatest News
FORTE Study News – November 2025
Join the quarterly FORTE site calls to hear updates on NRG-CC005 and discuss challenges and solutions with other research professionals working to enroll patients to this clinical trial.
Good Clinical Practices: The Pillars of Protocol Compliance and Patient Safety
Written by: Erin Zielinski, MS, CCRP Director of Research Operations, Department of Obstetrics, Gynecology and Women’s Health, University of Minnesota Medical School
NRG Oncology Trial of Sentinel Lymph Node Biopsy for Patients with Early-Stage Oral Cavity Cancer Re-opens to Phase III (NRG-HN006)
NRG Oncology recently reactivated the NRG-HN006 trial comparing sentinel lymph node (SLN) biopsy to elective neck dissection (END) for patients with early-stage oral cavity cancer. This trial completed phase II accrual in December 2024 and has since met the criteria to advance to the phase III portion of the trial.
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We are a leading protocol organizations within the National Clinical Trials Network and we seek to improve the lives of cancer patients by conducting practice-changing, multi-institutional clinical and translational research. Learn More