NRG-LU005 is a National Cancer Institute and NRG Oncology clinical trial to study if adding the immunotherapy drug called atezolizumab to the usual treatment of chemoradiotherapy can help lower the chance of small cell lung cancer growing or spreading and improve survival. Although the usual chemoradiotherapy treatment for this type of cancer does shrink the tumor in most cases, patients typically relapse quickly. Researchers believe that adding atezolizumab to chemoradiotherapy could improve the survival of patients with limited-stage small cell lung cancer. NRG-LU005 will compare the usual standard treatment to the same treatment plus atezolizumab. The goal is to determine if adding atezolizumab is as good as or better than the usual treatment.
More information about this particular study is located on ClinicalTrials.gov
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Additional information for the NRG Oncology LU005 trial can be found in the Patient Study Brochure
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Educational information on radiotherapy and lung cancer treatment can be found on this LUNGevity Foundation webpage.Visit the LUNGevity Website
Your healthcare team is the best source for information about your treatment options, including the ability to help you make the decision to participate in cancer clinical trials. Be sure to take the information you find to your doctor for discussion about possible studies and for questions and concerns.
Please talk to your healthcare team to see if there are other clinical studies that you may be a good fit for. Click here if you would like to view a more detailed chart of other studies available.
Below, you can find FAQs about clinical research and this particular clinical trial.
Doctors and researchers conduct a clinical study, also called a “clinical trial”, to find better ways to prevent, diagnose, or treat an illness. NRG Oncology is supported by the National Cancer Institute and runs clinical studies specifically for patients with cancer or to prevent cancer. Most clinical studies test something we know against something we don’t know. In all situations, these studies are strictly evaluated before they are allowed to be offered to any patient. The study is designed to answer the question that we do not know the answer to, so that current and future patients may have better treatments or information than what we currently have. There are different types of clinical studies that might be available for patients. For more information see “Types of Clinical Trials” and “Phases of Clinical Trials”.
At NRG Oncology, we focus on conducting clinical studies aimed to improve current cancer care practices and the lives of cancer patients. NRG Oncology partners with more than 1,300 member sites world-wide to research ways to improve treatment standards in the cancer community. Our organization is supported primarily through grants from the National Cancer Institute (NCI) and is one of five research groups in the NCI's National Clinical Trial's Network.