NRG-GI006 is a clinical trial that is studying proton therapy as the type of radiation treatment for this disease, to see if this treatment does or does not improve survival and decrease side effects when compared to the current usual treatment for people with esophageal cancer. Typically, the usual treatment for people who have this type of cancer is a combination of photon radiation therapy and chemotherapy followed by surgery. Proton therapy is a type of radiation therapy that uses protons, or positively charged particles, rather than x-rays to treat cancer. Both photon (x-ray) and proton therapies precisely deliver radiation to the tumor without damaging much of the tissue around it and have been tested for safety; however, researchers want to know if the proton based treatment works better than the other.
More information about this particular study is located on ClinicalTrials.gov
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Below, you can find FAQs about clinical research and this particular clinical trial.
Doctors and researchers conduct a clinical study, also called a “clinical trial,” to find better ways to prevent, diagnose, or treat an illness. NRG Oncology is supported by the National Cancer Institute (NCI) and runs clinical studies specifically for patients with cancer or to prevent cancer. Most clinical studies test something we know against something we don’t know. In all situations, these studies are strictly evaluated before they are allowed to be offered to any patient. The study is designed to answer the question that we do not know the answer to, so that current and future patients may have better treatments or information than what we currently have. There are different types of clinical studies that might be available for patients. For more information see “Types of Clinical Trials” and “Phases of Clinical Trials”.
Patients who volunteer to take part in a clinical study are followed closely by their health care professionals and members of the research team. For more information see “Research Team Members”.
At NRG Oncology, we focus on conducting clinical studies aimed to improve current cancer care practices and the lives of cancer patients. NRG Oncology partners with more than 1,300 member sites world-wide to research ways to improve treatment standards in the cancer community. Our organization is supported primarily through grants from the National Cancer Institute (NCI) and is one of five research groups in the NCI's National Clinical Trial's Network.