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John Coen MD
Closed to Accrual
To estimate the rate of distant metastasis at 3 years of two induction chemoradiotherapy regimens including 5-Fluorouracil, cisplatin, and BID irradiation (FCI) or gemcitabine and QD irradiation (GI). Induction chemoradiotherapy will be followed by radical cystectomy if the initial tumor response is incomplete or by consolidation chemoradiotherapy if the tumor has cleared, and both will be followed by adjuvant chemotherapy.
Data for this trial is being collected via the NRG/RTOG Data Center.
Operable Patients with muscularis propria invasion carcinoma of the bladder, all histologies - AJCC Stages T2-T4a, NX or N0, M0 - No histologic evidence of tumor invasion into the stroma of the prostate - No tumor-related hydronephrosis
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