July 15 2025
FORTE Enrolled its 3000th Participant on June 12, 2025!
Thank you to all FORTE investigators, clinical research professionals, nurses, phlebotomists, monitors, data analysts, regulatory professionals, and others for your efforts in enrolling participants in NRG-CC005. We would not be here without you.
IMPORTANT: FORTE Protocol Amendment #8
NRG-CC005 Amendment 8 (NCI Version Date: April 28, 2025) was activated on June 10, 2025, in the United States.
Please refer to the memorandum, dated June 10, 2025, posted under CIRB Approved Documents on CTSU for additional instructions and information.
REGISTER: FORTE Coordinator Session – July 29, 2025
The NRG Oncology FORTE team is excited to host the FORTE Coordinator Session with support from the FORTE Coordinator Committee. This virtual webinar will be at 12:00 pm ET on July 29, 2025, coinciding with the NRG Summer Meeting.
Register to hear from sites about enrollment best practices. Bring your questions about FORTE to this webinar on NRG-CC005. Topics may include:
- FORTE Update
- Screening for FORTE – POLYP 101
- Patient Outreach – mail, email, EMR, phone
- FORTE Introductory Phone Call – Best Practices
- Patient Reimbursement/Travel Allowance
- PRO Questionnaires/Sample Collection
- Rave Queries
- DQP Report
- Mobile Phlebotomy Overview
- Q&A Panel
Register for this virtual session today!
POLYP 101 Webinar –Recording and Slides
This FORTE Webinar presented by Dr. Jeffrey Dueker, Protocol Co-Chair, reviewed FORTE eligibility criteria. In this presentation, Dr. Dueker clarified that polyp size is estimated in the colonoscopy report, while pathology determines the type (histology) of the polyp.
Watch the recording on the FORTE YouTube channel on the FORTE | Research Professionals playlist. Slides can be found on CTSU.
Accrual Updates and Milestones (as of July 1, 2025)
Top accruing sites:
- Kaiser Permanente – Vallejo – 1561 accrued
- UPMC-Presbyterian Hospital – 320 accrued
- Regions Hospital – 141 accrued
Most recent randomizations:
- UCLA / Jonsson Comprehensive Cancer Center – July 1, 2025
- Yale University – July 1, 2025
- Case Western Reserve University – July 1, 2025
FORTE Top 25 Accruing Sites – July 1, 2025
FORTE Resource Portal
Bookmark this website, that organizes materials found on CTSU: https://www.nrgoncology.org/Clinical-Trials/NRG-CC005/FORTE-Resource-Portal. You will use the same login information as for CTSU to access this page. Once you gain access, the “FORTE Materials for Research Professionals” section contains many materials to assist you with accruing participants. This website also has contact information for questions you may have while working on NRG-CC005.
Find both CIRB-approved and protocol-related documents on CTSU under NRG-CC005.
Do you have new research team members working on NRG-CC005?
Clinical research professionals can sign up for NRG Weekly Broadcasts to receive FORTE Fridays updates directly to your inbox: https://www.nrgoncology.org/Home/News/Weekly-Broadcasts.
Questions from Site Research Staff
If research staff have questions about a patient's eligibility or study logistics for the NRG-CC005/FORTE Study, contact the Clinical Coordinating Department (CCD) at: FORTE@nrgoncology.org or 1(800) 477-7227.