Mark R. Gilbert, MD
Determine the maximum safe dose of single-agent treatment with ipilimumab, nivolumab and the combination when given with temozolomide during maintenance treatment for newly diagnosed glioblastoma.
Histopathologically proven diagnosis of glioblastoma or gliosarcoma prior to registration by pathology report. The tumor must be unifocal, confined to the supratentorial compartment and have undergone a gross total or near gross total resection.
This is a limited-institution study with pre-selected sites.
Activated April 16, 2015
The protocol and related documents will be available at NRG-BN002