Head and Neck Cancer Committee
Head and Neck Cancer Committee Leadership
Chair
Sue Yom, MD PhD
Vice Chair
Neil Hayes, MD
Vice Chair
Chris Holsinger, MD
Vice Chair
Trisha Wise-Draper, MD, PhD
Working Groups
Head and Neck Translational Working Group
Chair
Neil Hayes
Vice Chair
Sidharth Puram
H&N Surgery Working Group
Chair
Christopher Holsinger
H&N Skin Working Group
Chair
Shlomo Koyfman
Vice Chair
Christopher Barker
H&N Rare Tumor Working Group
Chair
Richard Bakst
Vice Chair
Stephen Lai
Previously Untreated Locally Advanced Working Group
Chair
Trisha Wise-Draper
Vice Chair
James Bates
H&N PRO-CE Working Group
Chair
Steven Chang
Vice Chair
Minh Tam Truong
H&N Recurrent-Metastatic Working Group
Chair
Dwight Heron
Vice Chair
Anna Spreafico
Core Committee Members
- Musaddiq Awan
- Julie Bauman
- Dukagjin Blakaj
- Scott V. Bratman
- Jimmy Caudell
- Bhisham Chera
- Jennifer H. Choe
- Christine Chung
- John De Almeida
- Neal Dunlap
- Thomas Galloway
- Neil Hayes
- Christina Henson
- Chris Holsinger
- Jed Katzel
- Jamie Ku
- Stephen Lai
- Nancy Lee
- Mihir Patel
- Sidharth V. Puram
- Shyam S.D. Rao
- James William Rocco
- Cristina Rodriguez
- Nabil Saba
- Michael A. Samuels
- Nicole C. Schmitt
- David Schwartz
- Jeffrey Shoop
- Heath Skinner
- Paul L. Swiecicki
- Vinita Takiar
- Samantha Tam
- Horatio Thomas
- John Waldron
- Trisha Wise-Draper
- Sue Yom
General Committee Members
- Nishant Agrawal
- Carryn Anderson
- Jennifer L. Anderson
- Anthony J. Apicelli, III
- Hani Ashamalla
- Vilija Avizonis
- Musaddiq Awan
- Samar Azawi
- Richard Bakst
- Sujith Baliga
- Brittany Barber
- Christopher A. Barker
- James E. Bates
- Beth M. Beadle
- Aashish Bhatt
- Mihir K. Bhayani
- Andrew C. Birkeland
- Alec Block
- Christopher L. Brett
- David Brizel
- Shauna Campbell
- Daniel R. Carrizosa
- Mark Chambers
- Douglas Chepeha
- Jennifer H. Choe
- Karen Y. Choi
- Farshad N. Chowdhury
- Francisco J. Civantos
- David A. Clump
- Kevin J. Contrera
- Pippa F. Cosper
- Jennifer Cracchiolo
- Roi Dagan
- Rushil R. Dang
- Jennifer F. De Los Santos
- Virginia Diavolitsis
- Jennifer A. Dorth
- Umamaheswar Duvvuri
- Heather A. Edwards
- Kyle S. Ettinger
- Daniel Faden
- Carole Fakhry
- Janice L. Farlow
- Rocco M. Ferrandino
- Robert L. Ferris
- David W.A. Forner
- Catherine H. Frenkel
- Christopher Fundakowski
- Muhammad Furqan
- Gregory Gan
- Ian Ganly
- Madhur K. Garg
- Adam A. Garsa
- Jessica Geiger
- Michael F. Gensheimer
- Maged Ghaly
- Laila A. Gharzai
- Michael Gibson
- Maura L. Gillison
- Emile Gogineni
- Evan M. Graboyes
- Jennifer H. Gross
- Neil Gross
- Craig Eli Grossman
- Alexander N. Hanania
- Richard A. Harbison
- Catherine T. Haring
- Molly E. Heft- Neal
- Dwight Heron
- Colin Hill
- Ryan T. Hughes
- Katherine A. Hutcheson
- Sachin R. Jhawar
- Chris Jones
- Richard Jordan
- Nikhil Joshi
- Aditya Juloori
- Anne C. Kane
- Hyunseok Kang
- Jung Julie Kang
- Sana Karam
- Vidhya Karivedu
- Rohan R. Katipally
- Saad Khan
- Ana Kiess
- Randall Kimple
- Kedar Shirish Kirtane
- Julie Kish
- Tim Kruser
- Jay J. Liao
- Miriam N. Lango
- Ryan M. Lanning
- Anh H. Le
- Steve Lee
- Anna Lee
- David Y. Lee
- Gary D. Lewis
- Christopher Lominska
- Bridgette Ma
- Daniel Ma
- Sung Jun Ma
- Sean S. Mahase
- Rafael Manon
- Emily J. Marchiano
- Charles Mayo
- Christopher McLaughlin
- Michelle Mierzwa
- Jacob A. Miller
- Dominic Moon
- Luc G.T. Morris
- Wojciech K. Mydlarz
- David Neskey
- Phuc Felix Nguyen-Tan
- Matthew Old
- Aru Panwar
- Henry S. Park
- Krupal Patel
- Mihir R. Patel
- Rusha Patel
- Cesar Perez
- Minh Phan
- Katharine Price
- Sidharth V. Puram
- Krishna Rao
- Mohammad Razaq
- Niema B. Razavian
- Jeremy Richmon
- Fahad Rind
- Jared Robbins
- Dylan F. Roden
- David M Routman
- Soumon Rudra
- Zeyad Sako
- Michael Samuels
- Vlad C. Sandulache
- Philip E. Schaner
- Nicole C. Schmitt
- Christopher Schultz
- David Schwartz
- Geroge Shenouda
- David J. Sher
- Eric Sherman
- Siddharth H. Sheth
- Lauren C. Shih
- Aditya Varnam Shreenivas
- Monica E. Shukla
- Kulbir Sidhu
- Andrew Sikora
- Anurag Singh
- Guy Slonimsky
- Matthew E. Spector
- Anna Spreafico
- William A. Stokes
- Erich Sturgis
- Rathan M. Subramaniam
- Baran D. Sumer
- Fangdi Sun
- John Sunwoo
- Krithika Suresh
- Samantha Tam
- Sewit Teckie
- Theodoros N. Teknos
- Carissa M. Thomas
- Toms Vengaloor Thomas
- Wade Thorstad
- Michael C. Topf
- Melanie E. Townsend
- Jillian Tsai
- Varun Vendra
- Matthew C. Ward
- Garrett T. Wasp
- Maurice Willis
- Stuart Wong
- Canhua Xiao
- George Q. Yang
- Justine Yang Bruce
- Min Yao
- Sun K. Yi
- Melissa R. Young
- Mehran Yusuf
- Mark E. Zafereo
- Kaveh Zakeri
- Dan Zandberg
- Anthony Zeitouni
- Joseph Zenga
- Jose P. Zevallos
- Simeng Zhu
- Zachary S. Zumsteg
| Study | Title | Status | Phase | Disease Category | Disease Site |
|---|---|---|---|---|---|
| NRG-CC013 |
A Randomized, Masked, Placebo Controlled, Phase II Trial Of Concurrent Chemoradiation With BMX-001 In Patients With Head And Neck Squamous Cell Carcinoma Receiving Concurrent Chemoradiation |
Open to Accrual | II | Head and Neck [HN] | Other |
| NRG-HN001 |
Randomized Phase II and Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA) |
Closed to Accrual & Treatment | II/III | Head and Neck [HN] | Head and Neck |
| NRG-HN002 |
A Randomized Phase II Trial for Patients with p16 Positive, Non-Smoking Associated, Locoregionally Advanced Oropharyngeal Cancer |
Terminated | II | Head and Neck [HN] | Head and Neck |
| NRG-HN003 |
A Phase I and Expansion Cohort Study of Adjuvant Cisplatin, Intensity-Modulated Radiotherapy, and MK-3475 (Pembrolizumab) in High-Risk Head and Neck Squamous Cell Carcinoma (HNSCC) |
Terminated | I | Head and Neck [HN] | Head and Neck |
| NRG-HN004 |
Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Locoregionally Advanced Head and Neck Cancer with a Contraindication to Cisplatin |
Terminated | II/III | Head and Neck [HN] | Head and Neck |
| NRG-HN005 |
A Randomized Phase II/III Trial of De-Intensified Radiation Therapy for Patients with Early-Stage, P16-Positive, Non-Smoking Associated Oropharyngeal Cancer |
Closed to Accrual & Treatment | II/III | Head and Neck [HN] | Head and Neck |
| NRG-HN006 |
Randomized Phase II/III Trial of Sentinel Lymph Node Biopsy Versus Elective Neck Dissection for Early-Stage Oral Cavity Cancer |
Open to Accrual | II/III | Head and Neck [HN] | Head and Neck |
| NRG-HN007 |
An Open-Label, Phase III Study of Platinum-Gemcitabine with or Without Nivolumab in the First-Line Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma |
Terminated | III | Head and Neck [HN] | Head and Neck |
| NRG-HN008 |
Phase I Trial with Expansion Cohort of DNA-PK Inhibition and IMRT in Cisplatin-Ineligible Patients with Stage 3-4 Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) |
Closed to Accrual & Treatment | I | Head and Neck [HN] | Head and Neck |
| NRG-HN009 |
Randomized Phase II/III Trial of Radiation with Cisplatin at 100 mg/m2 Every Three Weeks Versus Radiation with Weekly Cisplatin at 40 mg/m2 for Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN) |
Temporarily Closed to Accrual | II/III | Head and Neck [HN] | Head and Neck |
| NRG-HN010 |
A Phase II Trial of HER2-Targeted Therapies for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers |
Open to Accrual | II | Head and Neck [HN] | Head and Neck |
| NRG-HN011 |
A Randomized Phase II Study of Nivolumab Versus Nivolumab and BMS-986016 (Relatlimab) as Maintenance Treatment After First-Line Treatment with Platinum-Gemcitabine-Nivolumab for Patients with Epstein-Barr Virus-Associated Recurrent/Metastatic Nasopharyngeal Carcinoma (REMAIN) |
Open to Accrual | II | Head and Neck [HN] | Head and Neck |
| NRG-HN014 |
Randomized Phase III Trial of Neoadjuvant Immunotherapy with Response-Adapted Treatment Versus Standard-of-Care Treatment for Resectable Stage III/IV Cutaneous Squamous Cell Carcinoma (C-PRE) |
Open to Accrual | III | Head and Neck [HN] | Other |
| NRG-HN015 |
A Phase II Randomized Trial of Neoadjuvant Chemotherapy or Chemo-Immunotherapy in Patients with Recurrent/Persistent PD-L1 Enriched Squamous Cell Carcinoma of the Head and Neck Undergoing Salvage Surgery (NEOPOLIS) |
Open to Accrual | II | Head and Neck [HN] | Other |
| RTOG-0129 |
A Phase III Trial of Concurrent Radiation and Chemotherapy (Followed by Surgery for Residual Primary/N2-3 Nodal Disease) for Advanced Head and Neck Carcinomas |
Terminated | III | Head and Neck [HN] | Head and Neck |
| RTOG-0522 |
A Randomized Phase III Trial of Concurrent Accelerated Radiation and Cisplatin versus Concurrent Accelerated Radiation, Cisplatin, and Cetuximab C225 [Followed by Surgery for Selected Patients] for Stage III and IV Head and Neck Carcinomas |
Terminated | III | Head and Neck [HN] | Head and Neck |
| RTOG-0537 |
A Phase II/III Study Comparing Acupuncture-like Transcutaneous Electrical Nerve Stimulation (ALTENS) Versus Pilocarpine in Treating Early Radiation-Induced Xerostomia |
Terminated | II/III | Head and Neck [HN] | Head and Neck |
| RTOG-0615 |
A Phase II Study of Concurrent Chemoradiotherapy Using Three-Dimensional Conformal Radiotherapy (3D-CRT) or Intensity-Modulated Radiation Therapy (IMRT) + Bevacizumab (BV) For Locally or Regionally Advanced Nasopharyngeal Cancer |
Terminated | II | Head and Neck [HN] | Head and Neck |
| RTOG-0912 |
A Randomized Phase II Study of Concurrent Intensity Modulated Radiation Therapy (IMRT), Paclitaxel and Pazopanib (NSC 737754)/Placebo, for the Treatment of Anaplastic Thyroid Cancer |
Terminated | II | Head and Neck [HN] | Head and Neck |
| RTOG-0920 |
A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer |
Closed to Accrual & Treatment | III | Head and Neck [HN] | Head and Neck |
| RTOG-1008 |
A Randomized Phase II / Phase III Study of Adjuvant Concurrent Radiation and Chemotherapy Versus Radiation Alone in Resected High-Risk Malignant Salivary Gland Tumors |
Closed to Accrual & Treatment | II/III | Head and Neck [HN] | Head and Neck |
| RTOG-1016 |
Phase III Trial of Radiotherapy Plus Cetuximab Versus Chemoradiotherapy in HPV-Associated Oropharynx Cancer |
Terminated | III | Head and Neck [HN] | Head and Neck |
| RTOG-1216 |
Randomized Phase II/III Trial of Adjuvant Radiation Therapy with Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck |
Open to Accrual | II/III | Head and Neck [HN] | Head and Neck |
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