Brain Tumor Committee
Brain Tumor Committee Leadership
Chair
Minesh Mehta, MD
Vice Chair
Arnab Chakravarti, MD
Vice Chair
Mark Gilbert, MD
Vice Chair
Michael Vogelbaum, MD, PhD
Working Groups
IDHwt Glioma
IDHmut Glioma
Mets
Translational Science Brain Tumor Working Group
Chair
Arnab Chakravarti, MD
Core Committee Members
Core Committee Members
- Manmeet Ahluwalia
- Ken Aldape
- Drexell Hunter Boggs
- Paul D. Brown
- Stuart Burri
- Jennifer E. Cahill
- Arnab Chakravarti
- Michael Chan
- Prakash Chinnaiyan
- Mark Gilbert
- Vinai Gondi*
- Matthew Hall
- Jona Hattangadi-Gluth
- Virginia B. Hill
- Fabio Iwamoto
- Melin J. Khandekar
- Michelle Kim
- Jonathan Knisely
- Rupesh Kotecha
- Andrew Lassman
- Rimas Lukas
- Shearwood McClelland III
- Minesh Mehta
- Mark Mishra
- Yazmin Odia
- Joshua Palmer
- Vinay Puduvalli
- C. Leland Rogers
- Scott Soltys
- Paul Sperduto
- Jason Tharp*
- Theresa Thomas
- Daniel Trifiletti
- Christina Tsien
- Yoshie Umemura*
- Michael Vogelbaum
- Tony J.C. Wang
- Jeffrey S. Wefel
- Jonathan T. Yang
General Committee Members
- Jes Alexander
- Hani Ashamalla
- Albert Attia
- James Battiste
- Sasha Beyer
- Nicholas Blondin
- Deborah Blumenthal
- Daniela Bota
- Joseph Bovi
- Steve Braustein
- Andrew Brenner
- Daniel Cahill
- Arnab Chakravarti
- Serah Choi
- Yunfeng Cui
- Cristina DeCesaris
- Alexandra N. De Leo
- Mahua Dey
- Aidnag Diaz
- Michael Dominello
- Bently Doonan
- Nichole Fisher
- John Flickinger
- Matthew Gallitto
- Na Tosha Gatson
- Mark Gilbert
- Jon Glass
- Vinai Gondi
- Sharad Goyal
- Matthew M. Grabowski
- Sean Grimm
- Christian Grommes
- Shalina Gupta-Burt
- Jona Hattangadi-Gluth
- Grant Hunter
- Vikram Jairam
- Seok-Gu Kang
- William R. Kennedy
- Osaama Hassan Khan
- Deepak Khuntia
- Connor J. Kinslow
- Roman Kowalchuk
- Ryan D. Kraus
- Timothy Kruser
- Eric Lehrer
- Jian Yi Li
- Robert Liebross
- Christine Lu-Emerson
- Raymond M. Luke
- Sean S. Mahase
- Rachna Malani
- Mark Malkin
- Laurence Masson-Cote
- Adrianna H. Masters
- Minesh Mehta
- Eric A. Mellon
- Muhammad Altaf Memon
- Faina Nakhlis
- Mansoor Nasim
- Antonio Omuro
- Shiby Paul
- Haley Perlow
- Richard Peterson
- Huong Pham
- Luke R.G. Pike
- Paula Rauschkolb
- Raju Raval
- Kristin Redmond
- Benjamin J. Rich
- Charlotte I. Rivers
- Ian Robins
- Isabel Arrillaga-Romany
- David Routman
- Michael Rutenberg
- Sean Sachdev
- Anurag Saraf
- Christopher Schultz
- Soma Sengupta
- Nawal Shaikh
- Rohil Shekher
- Colette J. Shen
- Wenyin Shi
- Kevin R. Shiue
- Hui-Kuo Shu
- Raj Singh
- Lindsey Sloan
- Ashok Srinivasan
- John Suh
- Ashley Sumrall
- Jason Tharp
- Leonard Tuanquin
- Scott Turner
- Kenneth Usuki
- Prashant Vempati
- Michael Vogelbaum
- Kyle Wang
- Zabi Wardak
- Fangfang Yin
- Michael Yu
- Jim Zhong
- Jay-Jiguang Zhu
- Andrew H. Zureick
Committee Liaisons
Early Career Investigator Liaisons
- Vinai Gondi, MD
- Yoshie Umemura, MD
Patient Advocate Liaison
- Jason Tharp
| Study | Title | Status | Phase | Disease Category | Disease Site |
|---|---|---|---|---|---|
| NRG-BN002 |
Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed Glioblastoma |
Terminated | I | Brain [BN] | Malignant Glioma |
| NRG-BN003 |
Phase III Trial of Observation Versus Irradiation for a Gross Totally Resected Grade II Meningioma |
Open to Accrual | III | Brain [BN] | Benign Brain Tumors |
| NRG-BN005 |
A Phase II Randomized Trial of Proton Vs. Photon Therapy (IMRT) for Cognitive Preservation in Patients with IDH Mutant, Low to Intermediate Grade Gliomas |
Closed to Accrual & Treatment | II | Brain [BN] | Lower Grade Glioma |
| NRG-BN007 |
A Randomized Phase II/III Open-Label Study of Ipilimumab and Nivolumab Versus Temozolomide in Patients with Newly Diagnosed MGMT (Tumor O-6-Methylguanine DNA Methyltransferase) Unmethylated Glioblastoma |
Complete | II/III | Brain [BN] | Malignant Glioma |
| NRG-BN009 |
Phase III Trial of Stereotactic Radiosurgery (SRS) or Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for Distant Brain Relapse with Brain Metastasis Velocity >/= 4 Brain Metastases/Year |
Closed to Accrual | III | Brain [BN] | Other |
| NRG-BN010 |
A Safety Run-In and Phase II Study Evaluating the Efficacy, Safety, and Impact on the Tumor Microenvironment of the Combination of Tocilizumab, Atezolizumab, and Fractionated Stereotactic Radiotherapy in Recurrent Glioblastoma |
Closed to Accrual | II | Brain [BN] | Other |
| NRG-BN011 |
A Phase III Trial of Lomustine-Temozolomide Combination Therapy Versus Standard Temozolomide in Patients with Methylated MGMT Promoter Glioblastoma |
Open to Accrual | III | Brain [BN] | Malignant Glioma |
| NRG-BN012 |
A Randomized Phase III Trial of Pre-Operative Compared to Post-Operative Stereotactic Radiosurgery in Patients with Resectable Brain Metastases |
Closed to Accrual | III | Brain [BN] | Brain Metastases |
| NRG-BN013 |
Phase III Trial of Single Fraction Stereotactic Radiosurgery (SRS) Versus Fractionated SRS (FSRS) for Intact Brain Metastases |
Open to Accrual | III | Brain [BN] | Other |
| RTOG-0131 |
A Phase II Trial of Pre-Irradiation and Concurrent Temozolomide in Patients With Newly Diagnosed Anaplastic Oligodendrogliomas and Mixed Anaplastic Oligoastrocytomas |
Terminated | II | Brain [BN] | CNS Metastatic Disease |
| RTOG-0424 |
A Phase II Study of a Temozolomide-Based Chemoradiotherapy Regimen for High Risk Low-Grade Gliomas |
Terminated | II | Brain [BN] | Lower Grade Glioma |
| RTOG-0539 |
Phase II Trial of Observation for Low-Risk Meningiomas and of Radiotherapy for Intermediate- and High-Risk Meningiomas |
Terminated | II | Brain [BN] | Other |
| RTOG-0627 |
Phase II Trial of Dasatinib in Patients with Recurrent Glioblastoma Multiforme |
Terminated | II | Brain [BN] | Other |
| RTOG-0834 |
Phase III Trial on Concurrent and Adjuvant Temozolomide Chemotherapy in Non-1p/19q Deleted Anaplastic Glioma: The CATNON Intergroup Trial |
Terminated | III | Brain [BN] | Benign Brain Tumors |
| RTOG-0837 |
Randomized, Phase II, Double-Blind, Placebo-Controlled Trial of Conventional Chemoradiation and Adjuvant Temozolomide Plus Cediranib Versus Conventional Chemoradiation and Adjuvant Temozolomide Plus Placebo in Patients with Newly Diagnosed Glioblastoma |
Complete | II | Brain [BN] | Other |
| RTOG-0913 |
Phase I/II Trial of Concurrent RAD001 (Everolimus) with Temozolomide/Radiation Followed by Adjuvant RAD001/Temozolomide in Newly Diagnosed Glioblastoma |
Terminated | I/II | Brain [BN] | Other |
| RTOG-1114 |
Phase II Randomized Study of Rituximab, Methotrexate, Procarbazine, Vincristine, and Cytarabine with and Without Low-Dose Whole-Brain Radiotherapy for Primary Central Nervous System Lymphoma |
Terminated | II | Brain [BN] | Other |
| RTOG-1122 |
Phase II Double-Blinded Placebo-Controlled Study of Bevacizumab with or Without AMG 386 in Patients with Recurrent Glioblastoma or Gliosarcoma |
Terminated | II | Brain [BN] | Other |
| RTOG-1205 |
Randomized Phase II Trial of Concurrent Bevacizumab and Re-Irradiation Versus Bevacizumab Alone As Treatment for Recurrent Glioblastoma |
Terminated | II | Brain [BN] | Other |
| RTOG-9110 |
NCCTG 86-72-51: A Phase III Evaluation of Postoperative Radiation in Low Grade Intracranial Astrocytomas and Oligodendrogliomas |
Terminated | III | Brain [BN] | Other |
| RTOG-9402 |
Phase III Intergroup Randomized Comparison of Radiation Alone Vs Pre-Radiation Chemotherapy for Pure and Mixed Anaplastic Oligodendrogliomas |
Terminated | III | Brain [BN] | Other |
| RTOG-9802 |
A Phase II Study of Observation in Favorable Low-Grade Glioma and Phase III Study of Radiation With or Without PCV Chemotherapy in Unfavorable Low-Grade Glioma |
Terminated | II/III | Brain [BN] | Other |
| RTOG-9813 |
A Phase III (Phase I Closed) Randomized Study of Radiation Therapy and Temozolomide (IND #60,265) Versus Radiation Therapy and Nitrosourea for Anaplastic Astrocytoma and Mixed Anaplastic Oligoastrocytoma (Astrocytoma Dominant) |
Terminated | I/III | Brain [BN] | Other |
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