Genitourinary Cancer Committee
Genitourinary Cancer Committee Leadership
Chair
Paul L. Nguyen, MD
Vice Chair
Todd Morgan
Vice Chair
Phuoc Tho Tran
Vice Chair
Rana McKay, MD
Working Groups
Upfront Treatments for Prostate Cancer
Chair
Daniel Spratt
Post-operative Treatments for Prostate Cancer
Chair
William Hall
Bladder Cancer Therapy
Jason
Efstathiou
Renal Cancer Therapy
Chair
Rana McKay
New Investigator Working Group
Chair
Paul Nguyen
Translational Science GU Cancer
Chair
Phuoc Tran, MD, PhD
Core Committee Members
- Jean Paul Bahary
- Leslie Ballas
- Brian Baumann
- Ale Berlin
- Tom Boike
- Mark Buyyounski
- Ron Chen
- Deb Citrin
- Paul Crispen
- Scott Delacroix
- Neil Desai
- Dayssy Alexandra Diaz-Pardo
- Tanya Dorff
- Jason Efstathiou
- Rod Ellis
- Hiram Gay
- Bill Hall
- Dan Hamstra
- Andrea Hartszark
- Karen Hoffman
- I-Chow Joe Hsu
- Ashesh Jani
- Sophia Kamran
- Rojano Kashani
- Paul P. Koffer
- Bridget Koontz
- Dan Krauss
- Colleen Lawton
- Daniel J. Lee
- Jeffrey Lee
- Robert W. Lee
- Stanley Liauw
- Himu Lukka
- Ravi Madan
- David Marshall
- Rana McKay
- Cynthia Menard
- Dror Michaelson
- Jeff Michalski
- David Miyamoto
- Osama Mohamad
- Shalini Moningi
- Scott Morgan
- Todd Morgan
- Alicia Morgans
- Himanshu Nagar
- Thomas Ng
- Adam Olson
- J. Daniel Pennington
- Allan Pollack
- Ed Posadas
- Alan Dal Pra
- Adam Raben
- Dana Rathkopf
- Mack Roach
- Seth Rosenthal
- Ashley Ross
- Sean Sachdev
- Howard Sandler
- Oliver Sartor
- Tyler Seibert
- Xinglei Shen
- Jeff Simko
- Abhishek Solanki
- Daniel Y Song
- Catherine S. Spina
- Dan Spratt
- Chad Tang
- Phuoc Tho Tran
- Richard Valicenti
- Neha Vapiwala
- Robert Wallace
- Zach Zumsteg
General Committee Members
- Matthew C. Abramowitz
- Adanma Anji
- Hani Ashamalla
- Ayanambakkam Attanathi
- K.C. Balaji
- Alex Balogh
- Pedro Barata
- Rhonda Bitting
- Matthew J. Boyer
- Anna M. Brown
- Deborah Bruner
- Arnab Chakravarti
- Albert Chang
- Jonathan Chatzkel
- Richard Choo
- Hans Chung
- John Coen
- Mark Corkum
- Brett Cox
- Brian Cross
- Douglas Dahl
- Robert Den
- Israel Deutsch
- Vishal R Dhere
- Marie Duclos
- Libni Eapen
- Michael R. Folkert
- Aurelie Garant
- Jun Gong
- Sheela Hanasoge
- Raquibul Hannan
- Alan Hartford
- Comron J. Hassanzadeh
- Eric Horwitz
- Andrew J. Huang
- K. Saad Jahangir
- Vikram Jairam
- Bagi Jana
- James R. Janopaul-Naylor
- Skyler B. Johnson
- Gavin P. Jones
- Arash Rezazadeh Kalebasty
- Austin Kirschner
- Amar U. Kishan
- Christien A. Kluwe
- Lawrence Koutcher
- Timothy Kuzel
- Christopher Luminais
- Timothy D. Malouff
- Malcolm Mattes
- Michael J. McCormack, Jr.
- Neil Mendhiratta
- Anoop Meraney
- Joseph A. Miccio
- Mark V. Mishra
- Timur Mitin
- Gerard Morton
- Brian Myre
- Anthony T. Nguyen
- Krishnan Patel
- Ravi Patel
- Sagar A. Patel
- Houng Pham
- Ryan M. Phillips
- Luke Pike
- Thomas Pisansky
- Allan Pollack
- Thomas Pugh
- Rubina Qamar
- Anne W. Rajkumar
- Srinivas Raman
- Brian Ramnaraign
- Zachery R. Reichert
- Tyler Robin
- George Rodrigues
- Nikhil T. Sebastian
- Michael Seider
- Steven Seyedin
- Daniel Shasha
- Jay C. Shiao
- William Shipley
- Timothy Showalter
- Luis Souhami
- Shivani Sud
- Robin Toton
- Alfredo I Urdaneta
- Bhanu Prasad Venkatesulu
- Eric Vigneault
- Melinda Weiblen
- Michael J. Whalen
- Jessica M. Wilson
- Daniel X. Yang
- James Yu
- Nicholas Zaorsky
| Study | Title | Status | Phase | Disease Category | Disease Site |
|---|---|---|---|---|---|
| EA8185 |
ECOG-ACRIN/NRG Joint Study:A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, the INSPIRE Study |
Closed to Accrual | II | Genitourinary [GU] | Bladder |
| NRG-GU001 |
Randomized Phase II Trial of Postoperative Adjuvant IMRT Following Cystectomy for pT3/pT4 Urothelial Bladder Cancer |
Closed to Accrual | II | Genitourinary [GU] | Bladder |
| NRG-GU002 |
Phase II-III Trial of Adjuvant Radiotherapy and Androgen Deprivation Following Radical Prostatectomy with or Without Adjuvant Docetaxel |
Closed to Accrual | II/III | Genitourinary [GU] | Prostate |
| NRG-GU003 |
A Randomized Phase III Trial of Hypofractionated Post-Prostatectomy Radiation Therapy (HYPORT) Versus Conventional Post-Prostatectomy Radiation Therapy (COPORT) |
Terminated | III | Genitourinary [GU] | Prostate |
| NRG-GU005 |
Phase III IGRT and SBRT Vs IGRT and Hypofractionated IMRT for Localized Intermediate Risk Prostate Cancer |
Closed to Accrual & Treatment | III | Genitourinary [GU] | Prostate |
| NRG-GU006 |
A Phase II, Double-Blinded, Placebo-Controlled Randomized Trial of Salvage Radiotherapy with or Without Enhanced Anti-Androgen Therapy with Apalutamide in Recurrent Prostate Cancer |
Closed to Accrual & Treatment | II | Genitourinary [GU] | Prostate |
| NRG-GU007 |
Randomized Phase II Trial of Niraparib with Standard Combination Radiotherapy and Androgen DeprIvation Therapy (ADT) in High Risk Prostate Cancer (with Initial Phase I) (NADIR*) |
Complete | I/II | Genitourinary [GU] | Prostate |
| NRG-GU008 |
Randomized Phase III Trial Incorporating Apalutamide and Advanced Imaging into Salvage Treatment for Patients with Node-Positive Prostate Cancer After Radical Prostatectomy (INNOVATE*) *INtensifying treatment for NOde positive prostate cancer by VArying the hormonal ThErapy |
Closed to Accrual | III | Genitourinary [GU] | Prostate |
| NRG-GU009 |
Parallel Phase III Randomized Trials for High Risk Prostate Cancer Evaluating De-Intensification for Lower Genomic Risk and Intensification of Concurrent Therapy for Higher Genomic Risk with Radiation (PREDICT-RT*) |
Closed to Accrual | III | Genitourinary [GU] | Prostate |
| NRG-GU010 |
Parallel Phase III Randomized Trials of Genomic-Risk Stratified Unfavorable Intermediate Risk Prostate Cancer: De-Intensification And Intensification Clinical Trial Evaluation (GUIDANCE) |
Closed to Accrual | III | Genitourinary [GU] | Prostate |
| NRG-GU011 |
A Phase II Double-Blinded, Placebo-Controlled Trial of PROstate OligoMETastatic RadiotHErapy with or Without ANdrogen Deprivation Therapy in Oligometastatic Prostate Cancer (NRG Promethean) |
Closed to Accrual | II | Genitourinary [GU] | Prostate |
| NRG-GU012 |
Randomized Phase II Stereotactic Ablative Radiation Therapy (SABR) for Metastatic Unresected Renal Cell Carcinoma (RCC) Receiving Immunotherapy (SAMURAI) |
Open to Accrual | II | Genitourinary [GU] | Other |
| NRG-GU013 |
The Phase III ‘High Five Trial’ Five Fraction Radiation For High-Risk Prostate Cancer |
Open to Accrual | III | Genitourinary [GU] | Prostate |
| NRG-GU014 |
Randomized Phase II Trial of Pembrolizumab and Radiation vs. Radiation and Concurrent Chemotherapy for High-Grade T1 Bladder Cancer (PARRC Trial) |
Open to Accrual | II | Genitourinary [GU] | Bladder |
| NRG-GU015 |
The Phase III Adaptive Radiation and Chemotherapy for Muscle Invasive Bladder Cancer Trial (ARCHER) |
Open to Accrual | III | Genitourinary [GU] | Bladder |
| RTOG-0126 |
A Phase III Randomized Study of High Dose 3D-CRT/IMRT Versus Standard Dose 3D-CRT/IMRT in Patients Treated for Localized Prostate Cancer |
Terminated | III | Genitourinary [GU] | Prostate |
| RTOG-0232 |
A Phase III Study Comparing Combined External Beam Radiation and Transperineal Interstitial Permanent Brachytherapy with Brachytherapy Alone for Selected Patients with Intermediate Risk Prostatic Carcinoma |
Terminated | III | Genitourinary [GU] | Prostate |
| RTOG-0233 |
A Phase II Randomized Trial for Patients With Muscle-Invading Bladder Cancer Evaluating Transurethral Surgery and BID Irradiation Plus Either Paclitaxel and Cisplatin or 5-Fluorouracil and Cisplatin Followed by Selective Bladder Preservation and Gemcitabi |
Terminated | II | Genitourinary [GU] | Bladder |
| RTOG-0415 |
A Phase III Randomized Study of Hypofractionated 3D-CRT/IMRT Versus Conventionally Fractionated 3D-CRT/IMRT in Patients with Favorable-Risk Prostate Cancer |
Terminated | III | Genitourinary [GU] | Prostate |
| RTOG-0521 |
A Phase III Protocol of Androgen Suppression (AS) and 3DCRT/IMRT vs AS and 3DCRT/IMRT Followed by Chemotherapy with Docetaxel and Prednisone for Localized, High-Risk Prostate Cancer |
Terminated | III | Genitourinary [GU] | Prostate |
| RTOG-0524 |
A Phase I/II Trial of a Combination of Paclitaxel and Trastuzumab With Daily Irradiation or Paclitaxel Alone With Daily Irradiation Following Transurethral Surgery for Non-Cystectomy Candidates With Muscle-Invasive Bladder |
Terminated | I/II | Genitourinary [GU] | Bladder |
| RTOG-0526 |
A Prospective Phase II Trial of Transperineal Ultrasound-Guided Brachytherapy for Locally Recurrent Prostate Adenocarcinoma Following External Beam Radiotherapy |
Terminated | II | Genitourinary [GU] | Other |
| RTOG-0534 |
A Phase III Trial of Short Term Androgen Deprivation with Pelvic Lymph Node or Prostate Bed Only Radiotherapy (SPPORT) in Prostate Cancer Patients with a Rising PSA After Radical Prostatectomy |
Terminated | III | Genitourinary [GU] | Prostate |
| RTOG-0621 |
Adjuvant 3DCRT/IMRT in Combination with Androgen Suppression and Docetaxel for High Risk Prostate Cancer Patients Post-Prostatectomy: A Phase II Trial |
Terminated | II | Genitourinary [GU] | Other |
| RTOG-0712 |
A Phase II Randomized Study for Patients with Muscle-Invasive Bladder Cancer Evaluating Transurethral Surgery and Concomitant Chemoradiation by Either BID Irradiation Plus 5-Fluorouracil and Cisplatin or QD Irradiation Plus Gemcitabine Followed by Selective Bladder Preservation and Gemcitabine/Cisplatin Adjuvant Chemotherapy |
Terminated | II | Genitourinary [GU] | Bladder |
| RTOG-0815 |
A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy with or without Short-Term Androgen Deprivation Therapy for Patients with Intermediate-Risk Prostate Cancer |
Terminated | III | Genitourinary [GU] | Prostate |
| RTOG-0828 |
Pilot Project to Reduce Missing RTOG Quality of Life Data Via Electronic Web-Based Form Collection: A Companion Study for RTOG 0415 (A Phase III Randomized Study of Hypofractionated 3D-CRT/IMRT Versus Conventionally Fractionated 3D-CRT/IMRT in Patients wi |
Closed to Accrual | III | Genitourinary [GU] | Prostate |
| RTOG-0924 |
Androgen Deprivation Therapy and High Dose Radiotherapy with or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial |
Closed to Accrual & Treatment | III | Genitourinary [GU] | Prostate |
| RTOG-0926 |
A Phase II Protocol for Patients with Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent with Radiosensitizing Chemotherapy Following a Thorough Transurethral Surgical Re-Staging |
Terminated | II | Genitourinary [GU] | Bladder |
| RTOG-0938 |
A Randomized Phase II Trial of Hypofractionated Radiotherapy for Favorable Risk Prostate Cancer |
Terminated | II | Genitourinary [GU] | Prostate |
| RTOG-1115 |
Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) with a GNRH Agonist vs. Dose Escalated Radiation Therapy and Enhanced ADT with a GNRH Agonist and TAK-700 For Men with High Risk Prostate Cancer |
Terminated | III | Genitourinary [GU] | Prostate |
| RTOG-9408 |
A Phase III Trial of the Study of Endocrine Therapy used as a Cytoreductive and Cytostatic Agent Prior to Radiation Therapy in Good Prognosis Locally Confined Adenocarcinoma of the Prostate |
Terminated | III | Genitourinary [GU] | Prostate |
| RTOG-9601 |
A Phase III Trial of Radiation Therapy with or without Casodex in Patients with PSA Elevation Following Radical Prostatectomy for pT3N0 Carcinoma of the Prostate |
Terminated | III | Genitourinary [GU] | Prostate |
| RTOG-9910 |
A Phase III Trial to Evaluate the Duration of Neoadjuvant Total Androgen Suppression (TAS) and Radiation Therapy (RT) in Intermediate-Risk Prostate Cancer |
Terminated | III | Genitourinary [GU] | Prostate |
| S1806 |
SWOG/NRG Joint Study: Phase III Randomized Trial of Concurrent Chemoradiotherapy with or without Atezolizumab in Localized Muscle Invasive Bladder Cancer |
Closed to Accrual | III | Genitourinary [GU] | Bladder |
Support NRG Oncology.
Help Our Cause.
We are a leading protocol organizations within the National Clinical Trials Network and we seek to improve the lives of cancer patients by conducting practice-changing, multi-institutional clinical and translational research. Learn More