The FORTE Study

FORTE study is led by NRG Oncology and is a part of the National Clinical Trials Network (NCTN) program, which is sponsored by the National Cancer Institute (NCI).

FORTE is a colorectal cancer prevention study looking to determine how often participants who have had 1-2 small benign polyps removed during colonoscopy from their colon otherwise known as adenomatous polyps or adenomas should have repeat surveillance colonoscopies. The primary goal of FORTE is to compare the colorectal cancer rates between the two study groups (repeat colonoscopy at 5 and 10 years versus repeat colonoscopy at 10 years) to see if the rates are equivalent. If they are equivalent, then people in the future would likely be recommended to only undergo a 10-year exam and the 5-year exam may not be necessary. Participants will be asked to donate blood and stool samples and will be followed annually. 

The Clinical Coordinating Department (CCD) is available for ask protocol eligibility, clinical, and logistic questions related to the NRG-CC005/FORTE Protocol. Research professionals may contact the CCD via FORTE@nrgoncology.org or 1-800-477-7227. The CCD is available Monday through Friday from 8:30 am to 5:00 pm ET. Calls are returned the same business day if received before 4:30 pm ET.  Emails will be returned within one business day.

GI Professional Organizations Support Letter (AGA, ACG, ASGE)  

FORTE Letter for GI Practices