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      • NCORP Committees Overview
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      • Non-Disease Specific Committees Overview
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        • Developmental Therapeutics (DT) Overview
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      • Scientific Core Committees Overview
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        • Health Care Access (HCA) Overview
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        • Protocol Support Overview
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    • red icon of a clipboard with a medical + on it What is NRG Oncology
      • What is NRG Oncology Overview
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NRG Oncology
  • Patients

    • Patients Overview
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  • Our Research

    Our Research

    See our clinical trial portfolio as well as other areas of research conducted by NRG and our publication process.

    Our Research Overview
    • red icon of a clipboard with a medical + on it Clinical Trials
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    • red icon of a person reading a book or magazine Publications & Presentation Resources
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    The NRG Summer 2025 Semiannual Meeting will be held in person at the Marriott Marquis Hotel in Washington, D.C., from July 24, 2025 – July 26, 2025.

    Explore Resources
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    Search through all available NRG Oncology protocols and available materials.

    Find Trials
    • Research Resources Overview

      A compilation of all resources relevant to research conduct or reporting.

    • Ancillary Projects & Data Sharing

      Resources, contact information, applications, and review cycles for ancillary projects and data sharing.

    • Biospecimen Access

      How to request biospecimens collected from patients enrolled on NRG trials (and legacy groups GOG, NSABP, and RTOG).

    • Data Management Resources

      Data Management contact list, compiled resources for sites, and PRO resources.

    • DMC Charters and Minutes

      Data Monitoring Committee (DMC) Panels A, B, and C minutes are password protected (CTEP IAM/ID.me login).

    • Investigator Resources

      Investigator-specific resources or tools to aid in clinical trial participation or conduct.

    • Quality Assurance (QA) Resources

      Information and additional links to resources for NRG’s audit program.

    • Statistical Reports

      NRG trial statistical reports shared at NRG Semiannual Meetings.

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    Are you presenting on behalf of NRG Oncology? We have templates for presentations and posters for our research here.

    Find a Template
  • Committees

    Committees

    Our committees are a network of professionals with varying experience that come together to advance NRG’s research.

    Committees Overview
    • Leadership & Committee Openings
    • red icon of a book Oversight Committees
    • Disease Specific Committees
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    • red icon of a person reading a book or magazine Non-Disease Specific Committees
    • Scientific Core Committees
    • Administrative Committees

    NRG Oncology is comprised of several committees and subcommittees that conduct or support NRG trials.

    Find a Committee
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    • Oversight Committees Overview

      Committees charged with guiding, reviewing, evaluating, and implementing clinical trials in alignment with the NCTN.

    • Data Monitoring Committee

      Reviews the efficacy and morbidity data of trials to ensure decisions regarding these studies are ethically responsible.

    • Early Phase Trial Oversight Committee

      Oversees the group’s Phase I and non-randomized Phase II trials for safety and lead-in components of protocols.

    • Executive Committee

      Comprised of NRG leadership roles and tasked with setting priorities for the group.

    • Protocol Operations Management

      Monitors the progress of activated studies and assesses trial accrual as well as other trial performance metrics.

    • Research Strategy

      Focused on study development and providing feedback or recommendations to disease site and scientific core committees.

    • Disease Specific Committees Overview

      Comprised of 7 committees dedicated to the disease sites most commonly represented in NRG research.

    • Brain Tumor

      Focused on brain tumor research including primary and secondary tumors of the central nervous system.

    • Breast Cancer

      Focused on research aimed at improving the management and outcomes of breast cancer.

    • Gastrointestinal Cancer

      Comprised of colorectal and non-colorectal cancer sectors focused on reducing the burden of GI malignancies for patients.

    • Genitourinary Cancer

      Focused on improving outcomes in GU cancers including prostate, kidney. Bladder, & testicular cancers.

    • Gynecologic Cancer

      Oversees all gynecologic subcommittee cancer research efforts including clinical trial design and translational research.

    • Head and Neck Cancer

      Focused on research aimed at improving the management and outcomes of head & neck cancer.

    • Lung Cancer

      Focused on improving survival and quality of life for patients with non-metastatic lung cancer.

    • NCORP Committees Overview

      NRG NCORP includes committees that improve delivery, disease prevention & control, access & patient quality-of-life.

    • Cancer Care Delivery Research

      Improves clinical outcomes & patient well-being by minimizing factors that may influence care delivery.

    • Cancer Prevention & Control

      Prioritizes interventional studies to improve symptom burden or prevent cancer morbidity.

    • Health Care Access

      Assesses & eliminates differences in health care access to improve cancer care and outcomes.

    • Patient Centered Outcomes Research

      Assesses patient-reported outcomes in therapeutic and cancer control trials.

    • Non-Disease Specific Committees Overview

      Consists of four committees that conduct NRG trials and support research within the disease site committees.

    • Cancer Care Delivery Research

      Improves clinical outcomes & patient well-being by minimizing factors that may influence care delivery.

    • Cancer Prevention & Control

      Prioritizes interventional studies to improve symptom burden or prevent cancer morbidity.

    • Developmental Therapeutics (DT)

      Identifies dose, schedule & preliminary efficacy of novel therapeutic approaches on Phase I & II trials.

    • Patient Centered Outcomes Research

      Assesses patient-reported outcomes in therapeutic and cancer control trials.

    • Translational Science

      Provides translational science expertise to NRG trials & education on new technologies.

    • Scientific Core Committees Overview

      Consists of seven committees that serve as shared resources of expertise and technology for conducting our trials.

    • Health Care Access (HCA)

      Assesses & eliminates differences in health care access to improve cancer care and outcomes.

    • Imaging

      Charged with enhancing the use of imaging on NRG trials and evaluating new novel imaging for trials.

    • Medical Oncology

      Supports systemic treatments used in NRG trials.

    • Pathology

      Assists with the pathology components across disease sites on NRG trials.

    • Protocol Support

      Responsible for overseeing support and quality control of protocol-related activities.

    • Radiation Oncology

      Coordinates NRG’s radiation oncology-related activities for trials.

    • Surgical Oncology

      Focused on providing expertise on NRG trials that require surgical components in treatment.

    • Administrative Committees Overview

      Committees that manage efforts to build engagement, reach, & result reporting for clinical trials & information.

    • Ancillary Projects

      Responsible for the review & conduct of ancillary projects utilizing NRG data.

    • Communications

      Responsible for developing and disseminating content to members & the public regarding NRG trials & efforts.

    • Investigator & Career Development

      Focused on fostering investigator growth and engagement in NRG.

    • Membership

      Responsible for maintaining the process for which NRG members are accepted & operating within the group.

    • Patient Advocate Committee

      Advocates (patients/ caregivers) who partner with our researchers and liaison to their communities regarding research.

    • Publications

      Focused on releasing NRG results in a timely manner via journal publications, presentations, & more.

    • Gynecologic Cancer Overview

      Oversees all gynecologic subcommittee cancer research efforts including clinical trial design and translational research.

    • Cervix/Vulva Cancer Subcommittee

      Part of the GYN cancer committee umbrella. Focused on research pertaining to the cervix or vulva.

    • Ovarian Cancer Subcommittee

      Part of the GYN cancer committee umbrella. Focused on research pertaining to the ovaries.

    • Rare Tumor Subcommittee

      Part of the GYN cancer committee umbrella. Focused on rare cancer types & their biomolecular/genetic abnormalities.

    • Uterine Corpus Cancer Subcommittee

      Part of the GYN cancer committee umbrella. Focused on research pertaining to uterine malignancies.

    • Developmental Therapeutics (DT) Overview

      Identifies dose, schedule & preliminary efficacy of novel therapeutic approaches on Phase I & II trials.

    • DT Radiation Therapy Subcommittee

      Focuses on safety and efficacy of radiotherapy treatments in Phase I & II trials.

    • DT Gynecologic Phase I Subcommittee

      Focuses on safety and efficacy of therapeutics specific to Phase I gynecologic cancers.

    • Sarcoma Subcommittee

      Focuses on research pertaining to or correlating with sarcoma cancers.

    • Health Care Access (HCA) Overview

      Assesses & eliminates differences in health care access to improve cancer care and outcomes.

    • HCA Committee Events & Announcements

      HCA has several events, workshops, symposia & more to with varying topics and learning opportunities.

    • Imaging Overview

      Charged with enhancing the use of imaging on NRG trials and evaluating new novel imaging for trials.

    • Theranostics Subcommittee

      A collaboration of the Imaging & Radiation Oncology Committees for trials that include theranostics.

    • Medical Oncology Overview

      Supports systemic treatments used in NRG trials.

    • Immunotherapy Subcommittee

      Evaluates NRG concepts that utilize immunotherapy.

    • Pharmacy Subcommittee

      Supports NRG trials with pharmacy-specific input including drug information & toxicity management.

    • Protocol Support Overview

      Responsible for overseeing support and quality control of protocol-related activities.

    • CRA Subcommittee

      Advisory subcommittee helping facilitate the goals of the PSC specific to clinical research associates.

    • CTN Subcommittee

      Advisory subcommittee helping facilitate the goals of the PSC specific to clinical trial nurses.

    • Education & Training Subcommittee

      Develops educational programs for CRAs and CTNs in attendance at the NRG Meetings.

    • Mentorship Subcommittee

      Develops and refunds that CRA/CTN Mentorship Program.

    • Protocol Review Subcommittee

      Prospectively reviews protocols & major amendments for barriers & compliance.

    • Quality Control & Communication Subcommittee

      Identifies common audit issues, resolves data issues & distributes content through NRG Communications.

    • Radiation Oncology Overview

      Coordinates NRG’s radiation oncology-related activities for trials.

    • Medical Physics Subcommittee

      Composed of physicists with expertise in the development of technology employed in radiation therapy.

    • Theranostics Subcommittee

      A collaboration of the Imaging & Radiation Oncology Committees for trials that include theranostics.

    • Investigator & Career Development Overview

      Focused on fostering investigator growth and engagement in NRG.

    • Early Career Mentorship Subcommittee

      Committed to the inclusion of early-career investigators through the protocol development process.

    • Investigator Development Subcommittee

      Focused on expanding opportunities & engagement for investigators at all career levels.

    • Membership Overview

      Responsible for maintaining the process for which NRG members are accepted & operating within the group.

    • Canadian Members Subcommittee

      Focused specifically on the accrual & research aims for Canadian sites.

    • International Members Subcommittee

      Focused on accrual & research aims for international institutions.

    • Veteran Affairs/Military Treatment Facility Subcommittee

      Addresses research aims & obstacles specific to veteran and military treatment facilities.

  • About Us

    About Us

    NRG conducts multi-institutional phase II & III clinical trials as well as phase I & translational biological studies.

    About Us Overview
    • red icon of a clipboard with a medical + on it What is NRG Oncology
    • red icon of a book Policies and Bylaws
    • Organizational Overview
    • Membership
    • Education & Training
    • red icon of a person reading a book or magazine Mentorship Programs
    • red icon of a book Media & News
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    Make your voice heard. Join NRG and help us move the needle in cancer research.

    Register Here
    • What is NRG Oncology Overview

      Learn more about who we are and what our overarching organizational goals are as an NCI NCTN group.

    • Scientific Focus

      NRG has several scientific aims through our research. Learn more in our scientific focus section.

    • Legacy Groups

      NRG is comprised of three legacy groups. Learn more about our history & the three Foundations.

    • Support NRG

      Learn how you can be a part of our mission to improve outcomes for all impacted by cancer.

    • Contact Us

      Fill out our contact form or find specific contact information by department.

    Policies, guidelines, bylaws, and charters pertaining to our organization & research.

    View All
    • Organizational Overview

      This overview leads into the many sections and centers that work together under NRG to improve cancer outcomes.

    • Organizational Structure

      See the organizational charts the outline the multiple sections that keep NRG research moving forward.

    • Operations

      These offices help streamline the administrative and protocol development areas of our trials from start to finish.

    • SDMC

      The Statistics and Data Management Center provide expertise for design, conduct, and analysis of NRG trials.

    • NCORP (Overview & PIs)

      NRG’s NCI Community Oncology Research Program brings cancer trials to the community.

    • Biospecimen Bank

      NRG has Biospecimen Banks located in Columbus, Pittsburgh, and San Francisco. Learn more here.

    • Translational Science

      NRG’s translational science program intersects with all NRG clinical trial as well as ancillary projects.

    • CIRO

      The Center for Innovation in Radiation Oncology houses contouring atlases, templates, & tools to conduct research.

    • Membership Overview

      Includes Membership information, related documents or forms, requirements, and other applicable items.

    • Member Information Form

      All members are required to participate in our membership database form even if the response is opting out.

    • Membership Requirements

      Outline of membership categories including associated requirements & responsibilities.

    • Membership Applications & Roster Forms

      Information on how to apply for membership, make changes to your roster & who to contact for questions.

    • Membership Committee Reviews

      This password-protected area includes the content reviewed during Membership Committee meetings twice a year.

    • Member Institution Lists

      All available lists of member sites by type of member, location, CTEP ID, & voting members.

    • Education & Training Overview

      NRG offers educational materials and training courses for a variety of topics relevant to the conduct of our research.

    • CLASS Learning Modules

      Compliance, Learning, and SOP Solutions (CLASS) platform is a learning management system supported by CTSU.

    • Credentialing & Other Resources

      Contact information for RT & Imaging credentialing plus links to other important credentialing or trial resources.

    • VisionTree Training

      VisionTree platform, used on some NRG trials, hosts an NRG-VisionTree training webinar once a month.

    • Mentorship Programs Overview

      NRG is committed to the future of cancer research in all areas and levels of expertise through our mentorship programs.

    • Health Care Access Fellowship

      Health Care Access Fellowship

    • Early Career Mentored Fellowship Program

      NRG selects early-stage investigators via application process to be part of a mentored experience in trial development.

    • Clinical Research Coordinator Mentor Program

      Learn more about our CRC mentorship program and how to become a mentor or mentee.

    • Media & News Overview

      NRG has multiple sources of news including podcasts, newsletters, email broadcasts, and more.

    • Newsletters

      Archive of all NRG Currents newsletter editions. Each edition discusses a wide range of topics.

    • The NRG Oncology Podcast

      The NRG Oncology Podcast is an ongoing streaming podcast with new episodes each month.

    • Weekly Broadcasts

      NRG releases a weekly broadcast each Monday with all important updates on studies and other news.

  • Meetings

    • Meetings Overview
    • NRG Oncology 2026 Winter Meeting
    • Past NRG Meetings (past two years)
    • Future NRG Meetings
    • NRG Meeting Attendee Policies
    • Major Scientific Meetings

PSC Column: Cancer: No One is Immune

07/11/2024

Written and submitted by Judith O. Hopkins, MD; SCOR Principal Investigator, Novant Health Cancer Institute – Kernersville

Cancer doesn’t care who you are, what occupation you have or what type of lifestyle you lead. Cancer is an “equal opportunity” disease. Cancer first entered our lives 14 years ago when my husband was diagnosed with chronic lymphocytic leukemia (CLL) and started chemotherapy. As an oncologist, I was all too familiar with the side effects of chemotherapy induced fever, chills, neutropenia and fatigue. There were prophylactic antibiotics and frequent office visits. Friends made a huge difference with my husband’s therapy, sitting with him and transporting him home after therapy was completed.

July of 2015, I added cancer survivor to my resume. I received the call all women dread. “Your mammogram shows a nodule deep in your breast and you will need a biopsy.” The biopsy revealed invasive ductal breast cancer and I was started on letrozole, had a lumpectomy, and completed radiation therapy.

Too much knowledge of cancer and the toxicity of therapy can be challenging. I didn’t want radiation therapy and its small risk of lung or cardiac damage or the even smaller risk of angiosarcoma, but the benefits outweighed those risks and I proceeded with the recommended therapy. After 5 years I grappled with whether to stop letrozole or undergo extended endocrine therapy. I sought a second opinion at an academic medical center and accepted their recommendation to stop letrozole after 5 years.

We have tried to lead the recommended survivorship lifestyle over the ensuing years. My husband continues on oral chemotherapy which suppresses his immune system as does his CLL, and despite all the COVID vaccines, he took a birding trip and got COVID and nearly died, requiring a 2-week ICU stay and a ventilator and high flow oxygen. We stay away from red meat, eat at least 5 servings of fruits and vegetables daily, try to get 7.5 to 8 hours of sleep daily, and do not use tobacco, marijuana, vapor cigarettes, carbonated beverages, or drink alcohol.

Despite our 2 cancers, we have been BLESSED and are enjoying life! – Hop and Judy Hopkins

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