FORTE Study Update: June 2026

06/22/2026

Consent Withdrawal

Regarding NRG-CC005 Consent Withdrawals, participants are NOT to be withdrawn from the trial for the following reasons (these reasons are NOT criteria for Consent Withdrawal):

• Unable to contact the participant.
• The participant has moved.
• The participant is unwilling to comply with follow-up contact.
• The participant is unwilling to comply with randomized assignment of 5 and/or 10 years.
• After randomization, there is a clinical reason for the participant not to follow the randomized assignment of 5 and/or 10 years.

The Consent Withdrawal process should be followed only when the participant no longer wishes for his or her records to be included in the research project.

Consent Withdrawal applies when the participant does not wish to have any future data submitted to NRG Oncology. They not only refuse contact with the research team but also do not want their healthcare providers contacted or for passive follow-up to occur via review of the electronic medical record.

Consent withdrawal is the least preferred option and should be employed only when necessary. If a participant requests not to be contacted but will still allow data collection, that request can be accommodated without the withdrawal of consent. Many participants are comfortable with allowing the information they already provided, and information that can be further obtained without their being inconvenienced, to continue through other methods such as by accessing the electronic medical record or written correspondence with the participant. Other options should be offered before resorting to consent withdrawal.

Documentation and Reporting: 

If an unscheduled colonoscopy was performed that does not align with the randomized assignment of 5 or 10 years, submit the data related to this colonoscopy via Add Colonoscopy in the Colonoscopy Reports folder in RAVE.

If the participant refuses the 5 and/or 10-year colonoscopy, complete the Follow Up Colonoscopy Completion form in the “5 Year Colonoscopy” and/or “10 Year Colonoscopy” folder when it is due, documenting why the colonoscopy was missed/skipped or late.

Register: FORTE Coordinator Session – July 27, 2026

Save the date for the NRG 2026 Summer Meeting in Denver, CO. The meeting will be in-person, July 16-18, 2026, with select virtual sessions held during the week. If you plan to travel to Denver, the NRG FORTE team will be at the PSC Nurse/CRA Continuing Education Roundtables on Thursday afternoon to discuss protocol updates, data management, and best practices. FORTE updates will also be presented on Friday at the NCORP Townhall. The FORTE Workshop is returning in-person only to the NRG meeting on Friday, July 17, at 1 PM local time.

The FORTE Coordinator Session will then be hosted as a virtual webinar on July 27, 11 am ET, coinciding with the NRG Summer Meeting. Registration is open to hear from sites about enrollment best practices. This webinar will also be an excellent opportunity to have your FORTE-related questions answered by our panel of experts. Fill out this survey with your FORTE FAQs:

FORTE Coordinator Session FAQs Survey 

Register for the FORTE Coordinator Session

Register for the NRG Meeting

Accrual Updates and Milestones (as of May 1, 2026)

Top accruing sites:

• Kaiser Permanente – Vallejo – 2292 accrued
• UPMC-Presbyterian Hospital – 372 accrued
• Regions Hospital – 186 accrued

Most recent randomizations:

• Kaiser Permanente-Vallejo – June 1, 2026
• Yale University – June 1, 2026
• UCHealth University of Colorado Hospital – May 29, 2026
• Kansas City Veterans Affairs Medical Center – May 29, 2026
• Providence Veterans Administration Hospital – May 29, 2026
• George E Wahlen Department of Veterans Affairs Medical Center – May 29, 2026

FORTE Top 25 Accruing Sites – June 1, 2026

FORTE Resource Portal

Bookmark this website, that organizes materials found on CTSU: https://www.nrgoncology.org/Clinical-Trials/NRG-CC005/FORTE-Resource-Portal. You will use the same login information used for CTSU to access this page. Once you gain access, the “FORTE Materials for Research Professionals” section contains many materials to assist you with accruing participants. This website also has contact information for questions you may have while working on NRG-CC005.

Find both CIRB-approved and protocol-related documents on CTSU under NRG-CC005.

Do you have new research team members working on NRG-CC005?

Clinical research professionals can sign up for NRG Weekly Broadcasts to receive FORTE Fridays updates directly to your inbox: https://www.nrgoncology.org/Home/News/Weekly-Broadcasts.

Questions from Site Research Staff

If research staff have questions about a patient’s eligibility or study logistics for the NRG-CC005/FORTE Study, contact the Clinical Coordinating Department (CCD) at: FORTE@nrgoncology.org or 1(800) 477-7227.