‘COG-NRG ARST1321: Pazopanib Neoadjuvant Trial in Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC#737754; IND#118613)’ of page ‘COG-NRG ARST1321’
Principal Investigators COG: Aaron Weiss, DO NRG Oncology: Yen-Lin Chen, MD Primary Objectives To identify the dose of pazopanib that is feasible when given in combination with radiation or chemoradiation in pediatric and adult patients newly diagnosed with unresected intermediate- and high-risk NRSTS. To compare the rates of near complete pathologic response (> 90% necrosis) […]
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