RTOG-1014

A Phase II Study of Repeat Breast Preserving Surgery and 3D-Conformal Partial Breast Re-Irradiation (PBrI) for Local Recurrence of Breast Carcinoma

Principal Investigator

Douglas W. Arthur

Status

Disease Site

Breast [BR] Breast

Phase

II

Developmental Therapeutics

No

Primary Objective

To evaluate skin, breast, and chest wall adverse events occurring within 1 year from the completion of re-irradiation. 

Data Collection Notice:

Data for this trial is being collected via the NRG/RTOG Data Center.

 

Patient Population

 
• Histopathologic confirmation via lumpectomy of local in-breast ipsilateral recurrence

 

• Final breast surgery (lumpectomy and/or final re-excision) within 42 days prior to study entry;

 

• Initial lumpectomy followed by whole breast radiation >1 year prior to study entry;

 

• Bilateral breast mammogram and bilateral breast MRI within 120 days prior to study entry;

 

• Negative histologic margins of resection, no tumor on ink, following breast-preserving surgery of local recurrence

 

Target Accrual

61