RTOG-0631

Phase II/III Study of Image-Guided Radiosurgery/SBRT for Localized Spine Metastasis

Principal Investigator

Samuel Ryu

Status

Disease Site

Symptom Management [CC] Other

Phase

II/III

Developmental Therapeutics

No

Primary Objective

Phase II Component: Determine the feasibility of successfully delivering image-guided radiosurgery/SBRT for spine metastases in a cooperative group setting.Completed.

Phase III Component: Determine whether image-guided radiosurgery/SBRT (single dose of 16 Gy) improves pain control (as measured by the 11 point NRPS) as compared to conventional external beam radiotherapy (single dose of 8 Gy).

Data Collection Notice:

Data for this trial is being collected via the NRG/RTOG Data Center.

Patient Population

Patients with localized spine metastasis from the C1 to L5 levels (a solitary spine metastasis; 2 separate spine levels; or up to 3 separate sites); each of the separate sites must have a maximal involvement of 2 contiguous vertebral bodies.

Data Collection Notice:

Data for this trial is being collected via the NRG/RTOG Data Center.

Target Accrual

352