NSABP B-39 RTOG 0413

A Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) Versus Partial Breast Irradiation (PBI) for Women with Stage 0, I, or II Breast Cancer

Principal Investigator

Frank A. Vicini

Status

Disease Site

Breast [BR] Breast

Phase

III

Developmental Therapeutics

No

Primary Objective

To determine whether partial breast irradiation (PBI) limited to the region of the tumor bed following lumpectomy provides equivalent local tumor control in the breast compared to conventional whole breast irradiation (WBI) in the local management of early stage breast cancer.

Patient Population

Patients with Stage 0, I, or II Breast Cancer Resected by Lumpectomy; Tumor Size ≤ 3.0 cm; No More Than 3 Histologically Positive Nodes

Target Accrual

4214