NRG-LU005

Closed to Accrual & Treatment

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Protocol Information

Tab containing protocol details, study design, and eligibility criteria
Tab containing study documents, informed consent forms, and study materials
Tab containing information for potential study participants

Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase III Randomized Study of Chemoradiation Versus Chemoradiation Plus Atezolizumab

Principal Investigator

Kristin A. Higgins

Co-Principal Investigator(s)

Helen J. Ross

Status

Closed to Accrual & Treatment

Open to Accrual

May 28, 2019

Closed to Accrual

December 31, 2023

Closed to Accrual & Treatment

February 21, 2025


Disease Site

Lung [LU] Small Cell

Phase

III

Developmental Therapeutics

No

Primary Objective

To compare overall survival (OS) for patients with LS-SCLC treated with chemoradiation +/- atezolizumab.


Patient Population

Patients with pathologically (histologically or cytologically) proven diagnosis of limited stage (Tx, T1-T4, N0-3, M0) small cell lung cancer (LS-SCLC) who have received one pre-registration cycle of platinum/etoposide chemotherapy prior to study entry.

Target Accrual

506

Protocol Documents

Available via the National Cancer Institute (NCI) Cancer Trials Support Unit (CTSU) website.


Patient Study Webpage

To learn more about this study, visit the Patient Study Webpage.