NRG-GI008
Open to Accrual
Protocol Information
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-NORTH AMERICA)
Principal Investigator
Co-Principal Investigator(s)
Status
Open to Accrual
Open to Accrual
March 10, 2022
Disease Site
Gastrointestinal [GI] Colorectal
Phase
II/III
Developmental Therapeutics
No
Primary Objective
This Phase II/III trial will evaluate what kind of chemotherapy to
recommend to patients based on the presence or absences of circulating
tumor DNA (ctDNA) after surgery for colon cancer.
Patient Population
Men or women with Stage IIB, IIC, or Stage III colon cancer with R0 resection, and who are pMMR/MSS.
Target Accrual
1912
Protocol Documents
Available via the National Cancer Institute (NCI) Cancer Trials Support Unit (CTSU) website.
GI008 Video Interview with Drs. Dasari & George
GI008 Webinar with Natera (July 17, 2024)
Natera Tissue Return Request Template
Webinar: “Surgical implications of ctDNA: Is this the future for colon cancer?”
Patient Study Webpage
To learn more about this study, visit the Patient Study Webpage.