GOG-0278

Terminated

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Evaluation of Physical Function and Quality of Life (QOL) Before and After Non-Radical Surgical Therapy (Extra Fascial Hysterectomy or Cone Biopsy with Pelvic Lymphadenectomy) for Stage IA1 (LVSI+) and IA2-IB1 (=/<2CM) Cervical Cancer

Principal Investigator

Allan Covens, MD

Status

Terminated

Open to Accrual

October 1, 2012

Closed to Accrual

October 14, 2021

Closed to Accrual & Treatment

October 29, 2021

Complete

March 7, 2025

Terminated

March 7, 2025


Disease Site

Gynecologic [GY] Cervix

Phase

Other

Developmental Therapeutics

No

Primary Objective

To examine the changes before and after non-radical surgical treatment (simple hysterectomy or cone biopsy [fertility preservation]) and pelvic lymphadenectomy) on functional outcomes of bladder, bowel and sexual function for stage IA1 (LVSI+) and IA2-IB1 (<2cm) carcinoma of the cervix.

To evaluate incidence and severity of lymphedema after non-radical surgery (simple hysterectomy or cone biopsy [fertility preservation] and pelvic lymphadenectomy) for stage IA1 (LVSI+) and IA2-IB1 (<2cm) carcinoma of the cervix.

Patient Population

Patients with a histologic diagnosis of squamous cell carcinoma, adenocarcinoma or adenosquamous cell carcinoma of the cervix, Stage IA1 (LVSI+), IA2, and IB1 (tumor size [maximum visible or palpable]) ≤ 2cm), any grade.

Target Accrual

220

Patient Study Webpage

There is no available patient study webpage available for this trial at this time.