GOG-0229O

Terminated

Return to Protocol Table

Protocol Information

Tab containing protocol details, study design, and eligibility criteria
Tab containing study documents, informed consent forms, and study materials
Tab containing information for potential study participants

A Randomized Phase II with a Safety Lead-In to Assess the Antitumor Efficacy of the MEK Inhibitor Trametinib Alone or in Combination with GSK2141795, an AKT Inhibitor, in Patients with Recurrent or Persistent Endometrial Cancer NCT #01935973

Principal Investigator

Shannon Westin, MD

Status

Terminated

Open to Accrual

December 23, 2013

Closed to Accrual

July 18, 2015

Closed to Accrual & Treatment

August 9, 2015

Terminated

April 10, 2020


Disease Site

Gynecologic [GY] Uterine Corpus

Phase

I

Developmental Therapeutics

No

Primary Objective

To assess the relative activity of trametinib (MEK inhibitor) alone or in combination with GSK2141795 (AKT inhibitor) for patients with recurrent or persistent endometrial cancer by progression-free survival. 

Patient Population

Patients with recurrent or persistent endometrial cancer by progression-free survival.

Target Accrual

148

Patient Study Webpage

There is no available patient study webpage available for this trial at this time.