NRG-GI004

Closed to Accrual

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Protocol Information

Tab containing protocol details, study design, and eligibility criteria
Tab containing study documents, informed consent forms, and study materials
Tab containing information for potential study participants

Colorectal Cancer Metastatic dMMR/MSI-H Immuno-Therapy (COMMIT) Study: A Randomized Phase III Study of mFOLFOX6/Bevacizumab/Atezolizumab Combination Versus Single Agent Atezolizumab in the First-Line Treatment of Patients with Deficient DNA Mismatch Repair (dMMR)/Microsatellite Instability-High (MSI-H) Metastatic Colorectal Cancer

Status

Closed to Accrual

Open to Accrual

November 7, 2017

Temporarily Closed to Accrual

June 4, 2020

Open to Accrual

January 29, 2021

Temporarily Closed to Accrual

March 31, 2025

Closed to Accrual

September 2, 2025


Disease Site

Brain [BN] Other

Phase

III

Developmental Therapeutics

Yes

Target Accrual

347

Protocol Documents

Available via the National Cancer Institute (NCI) Cancer Trials Support Unit (CTSU) website.


Patient Study Webpage

There is no available patient study webpage available for this trial at this time.