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NRG-LU001

NRG-LU001: Randomized Phase II Trial of Concurrent Chemoradiotherapy +/- Metformin HCL in Locally Advanced NSCLC; ClinicalTrials.gov NCT02186847

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Principal Investigators   

 Theodoros (Theos) Tsakiridis, MD

 Heath Skinner, MD, PhD

Primary Objective

To determine whether metformin added to chemoradiotherapy can improve progression-free survival in patients with locally advanced NSCLC

Patient Population

Pathologically proven diagnosis of Stage IIIA or IIIB non-small cell lung cancer; patients must have unresectable disease, be medically inoperable, or not willing to undergo surgical management.

Target Accrual

168 patients

Status

Activated  August  25, 2014

Protocol Documents

 The protocol and related documents are available at NRG-LU001

 




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